Description: BIO 1211 is a selective and high affinity inhibitor of ?4?1 with IC50 value of 0.004uM .The leukocyte integrin ?4?1 mediates leukocyte recruitment, activation, apoptosis inhibition and mediator release, it plays an important role in inflammatory responses .
Description: BIO5192 is a small molecule inhibitor of integrin ?4?1 with an IC50 value of 1.8 ± 0.7 nM .Integrin ?4?1 is important in inflammatory processes.
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