Description: A sandwich quantitative ELISA assay kit for detection of Human Leucine Rich Repeat Kinase 2 (LRRK2) in samples from tissue homogenates, cell lysates or other biological fluids.
Description: A sandwich quantitative ELISA assay kit for detection of Human Leucine Rich Repeat Kinase 2 (LRRK2) in samples from tissue homogenates, cell lysates or other biological fluids.
Description: A polyclonal antibody against LRRK2. Recognizes LRRK2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
Description: A polyclonal antibody against LRRK2. Recognizes LRRK2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
Description: A polyclonal antibody against LRRK2. Recognizes LRRK2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Description: A polyclonal antibody for detection of LRRK2 from Human, Mouse. This LRRK2 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human LRRK2 protein
Description: A polyclonal antibody for detection of LRRK2 from Human, Mouse. This LRRK2 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human LRRK2 protein
Description: A polyclonal antibody for detection of LRRK2 from Human, Mouse. This LRRK2 antibody is for IHC-P. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human LRRK2 protein
Description: LRRK2-IN-1 is a potent and selective inhibitor of LRRK2 with IC50 value of 13 nM. [1]LRRK2 (Leucine-rich repeat kinase 2) is also known dardarin. LRRK2 belongs to the leucine-rich repeat kinase family.
Description: LRRK2-IN-1 is a potent and selective inhibitor of LRRK2 with IC50 value of 13 nM. [1]LRRK2 (Leucine-rich repeat kinase 2) is also known dardarin. LRRK2 belongs to the leucine-rich repeat kinase family.
Description: LRRK2-IN-1 is a potent and selective inhibitor of LRRK2 with IC50 value of 13 nM. [1]LRRK2 (Leucine-rich repeat kinase 2) is also known dardarin. LRRK2 belongs to the leucine-rich repeat kinase family.
Description: LRRK2-IN-1 is a potent and selective inhibitor of LRRK2 with IC50 value of 13 nM. [1]LRRK2 (Leucine-rich repeat kinase 2) is also known dardarin. LRRK2 belongs to the leucine-rich repeat kinase family.
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LRRK2 . This antibody is tested and proven to work in the following applications:
Description: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Description: A polyclonal antibody against LRRK2. Recognizes LRRK2 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody against LRRK2. Recognizes LRRK2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody against LRRK2. Recognizes LRRK2 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARK8 (LRRK2) (E519). This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARK8 (LRRK2) (L893). This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARK8 (LRRK2) (L899). This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human LRRK2 (C-Terminus). This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PARK8 (LRRK2) (L955). This antibody is tested and proven to work in the following applications:
Description: Description of target: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 33 pg/mL
Description: Description of target: Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Phosphorylates PRDX3. Has GTPase activity.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: 8.59 pg/mL
Description: Description of target: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.078 ng/mL
Description: Description of target: Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Phosphorylates PRDX3. Has GTPase activity.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.082 ng/mL
Description: Description of target: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 31pg/mL
Description: The substance CZC 54252 Hydrochloride is a lrrk2 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 100 mM in DMSO.
Description: The substance CZC 54252 Hydrochloride is a lrrk2 inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 100 mM in DMSO.
Description: A monoclonal antibody from clone S231B-34 against Human LRRK2/Dardarin. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat.
Description: A monoclonal antibody from clone S231B-34 against Human LRRK2/Dardarin. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat.
Description: A monoclonal antibody from clone S231B-34 against Human LRRK2/Dardarin. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat.
Description: A monoclonal antibody from clone S231B-34 against Human LRRK2/Dardarin. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat.
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 ELISA Kit)
)
)
 Antibody)
 Antibody)
 ELISA Kit)
 Antibody (E519))
 Antibody (L893))
 Antibody (L899))
)
 Antibody (L955))
 LRRK2-/-)
 (OKAN06632))
 (OKCA02403))
 (OKCD04241))
 (OKEH04209))
 (OKEH05425))
 (pORF))
 (OKCD09087))
 (pORF))
 (pORF))
)
