Description: N-terminal fragment of protease-activated receptor 4 (PAR4) that acts as a PAR4 agonist (EC50 ~ 100 ?M). Induces platelet aggregation and annexin V activation with no effect on clotting time. Mimics thrombin-induced increases in IL-8/CXCL8-Luc activity an
Description: 6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonist.Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons.
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