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AS160 antibody
70R-31337
Fitzgerald 100 ug
Description: Rabbit polyclonal AS160 antibody
AS160 antibody
70R-50753
Fitzgerald 100 ul
Description: Purified Polyclonal AS160 antibody
AS160 Antibody
AF4682
Affbiotech 200ul
Description: AS160 Antibody detects endogenous levels of AS160.
AS160 Antibody
AF7630
Affbiotech 200ul
Description: AS160 Antibody detects endogenous levels of AS160.
AS160 Antibody
AF7631
Affbiotech 200ul
Description: AS160 Antibody detects endogenous levels of AS160.
AS160 antibody
PAab09889
Lifescience Market 100 ug
Anti-Phospho-TBC1D4-(S588) antibody
STJ117888
St John's Laboratory 100 µl
Description: This gene is a member of the Tre-2/BUB2/CDC16 domain family. The protein encoded by this gene is a Rab-GTPase-activating protein, and contains two phopshotyrosine-binding domains (PTB1 and PTB2), a calmodulin-binding domain (CBD), a Rab-GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin-dependent trafficking of the glucose transporter 4 (GLUT4), important for removing glucose from the bloodstream into skeletal muscle and fat tissues. Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane, suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions. When exposed to insulin, this protein is phosphorylated, dissociates from GLUT4 vesicles, resulting in increased GLUT4 at the cell surface, and enhanced glucose transport. Phosphorylation of this protein by AKT is required for proper translocation of GLUT4 to the cell surface. Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion. Alternative splicing results in multiple transcript variants encoding different isoforms.
AS160 antibody (Thr642)
70R-31336
Fitzgerald 100 ug
Description: Rabbit polyclonal AS160 antibody (Thr642)
AS160/TBC1 Antibody
3954-100
Biovision
AS160/TBC1 Antibody
3954-30T
Biovision

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