|
|
DLR-ACTH-c-48T
|
DL Develop |
|
48T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
DLR-ACTH-c-96T
|
DL Develop |
|
96T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
DLR-ACTH-g-48T
|
DL Develop |
|
48T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
|
|
|
|
DLR-ACTH-g-96T
|
DL Develop |
|
96T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
|
|
|
|
DLR-ACTH-Hu-48T
|
DL Develop |
|
48T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
DLR-ACTH-Hu-96T
|
DL Develop |
|
96T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
DLR-ACTH-Mu-48T
|
DL Develop |
|
48T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
DLR-ACTH-Mu-96T
|
DL Develop |
|
96T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
DLR-ACTH-Ra-48T
|
DL Develop |
|
48T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
DLR-ACTH-Ra-96T
|
DL Develop |
|
96T |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Adrenocorticotropic Hormone (ACTH) in samples from serum, plasma or other biological fluids.
|
|
|
|
RD-ACTH-c-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RD-ACTH-c-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RD-ACTH-g-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RD-ACTH-g-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RD-ACTH-Hu-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RD-ACTH-Hu-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RD-ACTH-Mu-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RD-ACTH-Mu-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RD-ACTH-Ra-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RD-ACTH-Ra-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RDR-ACTH-c-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RDR-ACTH-c-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RDR-ACTH-g-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RDR-ACTH-g-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RDR-ACTH-Hu-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RDR-ACTH-Hu-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RDR-ACTH-Mu-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RDR-ACTH-Mu-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
RDR-ACTH-Ra-48Tests
|
Reddot Biotech |
|
48 Tests |
|
|
|
RDR-ACTH-Ra-96Tests
|
Reddot Biotech |
|
96 Tests |
|
|
|
|
|
|
|
10-2353
|
Fitzgerald |
|
500 ug |
Description: Mouse Monoclonal ACTH antibody
|
|
|
|
10-2850
|
Fitzgerald |
|
1 mg |
Description: Mouse Monoclonal ACTH antibody
|
|
|
|
10-A31A
|
Fitzgerald |
|
1 mg |
Description: Mouse monoclonal ACTH antibody
|
|
|
|
10-A32A
|
Fitzgerald |
|
1 mg |
Description: Mouse monoclonal ACTH antibody
|
|
|
|
30R-2419
|
Fitzgerald |
|
2 mg |
Description: Synthetic ACTH protein
|
|
|
|
20R-2533
|
Fitzgerald |
|
250 uL |
Description: Rabbit polyclonal Adrenocorticotropic Hormone antibody
|
|
|
|
R31470
|
NSJ Bioreagents |
|
100 ug |
|
|
|
55R-SDX018
|
Fitzgerald |
|
96 wells |
Description: ELISA kit for detection of ACTH in the research laboratory
|
|
|
|
5-00584
|
CHI Scientific |
|
4 x 5mg |
|
|
|
5-00587
|
CHI Scientific |
|
4 x 5mg |
|
|
|
5-00594
|
CHI Scientific |
|
4 x 5mg |
|
|
|
5-00598
|
CHI Scientific |
|
4 x 1mg |
|
|
|
5-00600
|
CHI Scientific |
|
4 x 5mg |
|
|
|
5-00602
|
CHI Scientific |
|
4 x 5mg |
|
|
|
5-00603
|
CHI Scientific |
|
4 x 5mg |
|
|
|
5-00605
|
CHI Scientific |
|
4 x 5mg |
|
|
|
|
|
HY-P1503
|
MedChemExpress |
|
5mg |
|
|
|
HY-P1545
|
MedChemExpress |
|
10mg |
|
|
|
HY-P1555
|
MedChemExpress |
|
10mg |
|
|
|
HY-P1558
|
MedChemExpress |
|
5mg |
|
|
|
HY-P1582
|
MedChemExpress |
|
10mg |
|
|
|
HY-P1603
|
MedChemExpress |
|
1mg |
|
|
|
H-6050.0001
|
Bachem |
|
1.0mg |
Description: Sum Formula: C89H133N25O22S; CAS# [5576-42-1] net
|
|
|
|
H-6050.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C89H133N25O22S; CAS# [5576-42-1] net
|
|
|
|
H-7708.0001
|
Bachem |
|
1.0mg |
Description: Sum Formula: C77H109N21O20S; CAS# [25696-21-3] net
|
|
|
|
H-7708.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C77H109N21O20S; CAS# [25696-21-3] net
|
|
|
|
H-2898.0001
|
Bachem |
|
1.0mg |
Description: Sum Formula: C90H125N19O32; CAS# [37548-29-1]
|
|
|
|
H-2898.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C90H125N19O32; CAS# [37548-29-1]
|
|
|
|
H-1125.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C20H30N4O8S; CAS# [19405-50-6]
|
|
|
|
H-1125.0025
|
Bachem |
|
25.0mg |
Description: Sum Formula: C20H30N4O8S; CAS# [19405-50-6]
|
|
|
|
H-1130.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C59H78N16O16S; CAS# [2791-05-1] net
|
|
|
|
H-1130.0025
|
Bachem |
|
25.0mg |
Description: Sum Formula: C59H78N16O16S; CAS# [2791-05-1] net
|
|
|
|
H-1135.0001
|
Bachem |
|
1.0mg |
Description: Sum Formula: C75H106N20O19S; CAS# [22006-64-0]
|
|
|
|
H-1135.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C75H106N20O19S; CAS# [22006-64-0]
|
|
|
|
H-1140.0001
|
Bachem |
|
1.0mg |
Description: Sum Formula: C77H109N21O20S; CAS# [25696-21-3] net
|
|
|
|
H-1140.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C77H109N21O20S; CAS# [25696-21-3] net
|
|
|
|
H-1145.0001
|
Bachem |
|
1.0mg |
Description: Sum Formula: C95H145N29O23S; CAS# [7266-47-9]
|
|
|
|
H-1145.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C95H145N29O23S; CAS# [7266-47-9]
|
|
|
|
H-1180.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C44H59N13O10S; CAS# [4037-01-8] net
|
|
|
|
H-1180.0025
|
Bachem |
|
25.0mg |
Description: Sum Formula: C44H59N13O10S; CAS# [4037-01-8] net
|
|
|
|
H-1210.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C77H134N24O16; CAS# [4237-93-8]
|
|
|
|
H-1210.0025
|
Bachem |
|
25.0mg |
Description: Sum Formula: C77H134N24O16; CAS# [4237-93-8]
|
|
|
|
H-1220.0005
|
Bachem |
|
5.0mg |
Description: Sum Formula: C37H50N6O9; CAS# [69454-10-0]
|
|
|
|
H-1220.0025
|
Bachem |
|
25.0mg |
Description: Sum Formula: C37H50N6O9; CAS# [69454-10-0]
|
|
|
|
STJ500036
|
St John's Laboratory |
|
100 µg |
|
|
|
STJ16100288
|
St John's Laboratory |
|
100 µg |
|
|
|
STJ16100830
|
St John's Laboratory |
|
1 mg |
|
|
|
STJ16101193
|
St John's Laboratory |
|
250 µl |
|
|
|
STJ16101316
|
St John's Laboratory |
|
1 mL |
|
|
|
STJ16101452
|
St John's Laboratory |
|
1 mL |
|
|
|
STJ180333
|
St John's Laboratory |
|
0.1 ml |
|
|
|
|
|
RQ4873
|
NSJ Bioreagents |
|
100ul |
|
|
|
V8807-100UG
|
NSJ Bioreagents |
|
100ug |
Description: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.
|
|
|
|
V8807-20UG
|
NSJ Bioreagents |
|
20ug |
Description: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.
|
|
|
|
V8807SAF-100UG
|
NSJ Bioreagents |
|
100ug |
Description: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.
|
|
|
|
V8938-100UG
|
NSJ Bioreagents |
|
100ug |
Description: POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V8938-20UG
|
NSJ Bioreagents |
|
20ug |
Description: POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V8938SAF-100UG
|
NSJ Bioreagents |
|
100ug |
Description: POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V9067-100UG
|
NSJ Bioreagents |
|
100 ug |
Description: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V9067-20UG
|
NSJ Bioreagents |
|
20 ug |
Description: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V9067SAF-100UG
|
NSJ Bioreagents |
|
100 ug |
Description: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V3191-100UG
|
NSJ Bioreagents |
|
100 ug |
Description: ACTH (or Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 25-39) and does not react with Synacthen (aa 1-24). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V3191-20UG
|
NSJ Bioreagents |
|
20 ug |
Description: ACTH (or Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 25-39) and does not react with Synacthen (aa 1-24). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V3191SAF-100UG
|
NSJ Bioreagents |
|
100 ug |
Description: ACTH (or Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 25-39) and does not react with Synacthen (aa 1-24). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V3192-100UG
|
NSJ Bioreagents |
|
100 ug |
Description: ACTH (or Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 25-39) and does not react with Synacthen (aa 1-24). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|
|
|
V3192-20UG
|
NSJ Bioreagents |
|
20 ug |
Description: ACTH (or Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 25-39) and does not react with Synacthen (aa 1-24). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
|
|