A monoclonal antibody from clone 12A9 against Human | Mouse | Rat CD45. The host species for the production of this antibody is Mouse. The antigen used for immunization is Human Purified recombinant fragment of human CD45 expressed in E. Coli. The antibody is tested and validated for WB, IHC assays with the following recommended dilutions: WB (1:1000). This MAb for CD45 is conjugated with Alkaline Phosphatase.
CD45 is a 180-240 kD glycoprotein, also known as the leukocyte common antigen (LCA), T200 or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, broadly expressed amount hematopoietic cells. There are kmultiple isoforms of CD45 distributed throughout the immune system, and they arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell, as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
- Shipped on ice packs at +4ºC . Upon receiving the antibody store it at -20ºC.
- The gross weight of the package is 1.4 kg. and the net weight of the product is 0.1 grams.
- The item is not hazardous according to both ADR and UN. Its tariff code is 3002.15.0000 (Immunological products, put up in measured doses or in forms or packings for retail sale). The UNSPSC code of the product is 12352203 (Antibodies).
This product is not for human or animal treatment or consumption. Not for use in diagnostics or therapeutics. For in vitro research use only.
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