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Prostaglandin E2 EIA Kit

Supplier Stressmarq · Catalog number: SKT-207-96

Price

527.00EUR

Size
1 plate of 96 wells

Sandwich EIA kit used for quantitative measuring PGE2 present in Saliva, Urine, Serum, EDTA Plasma, Heparin Plasma, Tissue Culture Media samples from all species

  • Additional information:Eicosanoid signal transduction pathways are highly conserved and are involved in a number of physiological processes. Prostaglandins are synthesized from arachidonic acid by cyclooxygenase (COX)-1 or -2, which convert the acid into PGH2. This is further processed by cytosolic or microsomal prostaglandin synthases to become PGE2 or one of several other prostanoids (1-3). Prostacyclin is the major cyclooxygenase product in blood vessel walls and it is present in inflammatory fluids in similar concentrations to PGE2. Prostacyclin is a potent vasodilator and is more potent than PGE2 in producing hyperalgesia (4). PGE2 is produced by a wide variety of tissues (5-12) and in several pathological conditions, including inflammation, arthritis, fever, tissue injury, endometriosis, and a variety of cancers (5,6). Other biological actions of PGE2 include vasodilation, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption, and has thermoregulatory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics (7-12).
  • Storage and shipping:The kit is transported on ice packs (+4ºC). Upon receipt store at -20ºC. Non-hazardous item according to both ADR and UN regulations.
  • Notes:For research use only. Not to be used for human or animal treatment or diagnostics.

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