Description of target: In the field of cell biology, TNF-related apoptosis-inducing ligand (TRAIL), is a protein which functions as a ligand which induces the process of cell death called apoptosis. TRAIL has also been designated CD253 (cluster of differentiation 253).Tumor necrosis factor (TNF) family cytokines function as prominent mediators of immune regulation and the inflammatory response. Most TNF family cytokines are expressed as type II transmembrane proteins, with homology confined to approximately 150 C-terminal residues. The TNF ligands interact with a parallel family of receptors. TRAIL binds to the death receptors DR4 (TRAIL-RI) and DR5 (TRAIL-RII). The process of apoptosis is caspase-8-dependent. Caspase-8 activates downstream effector caspases including procaspase-3, -6, and -7, leading to activation of specific kinases. TRAIL also binds the receptors DcR1 and DcR2, which do not contain a cytoplasmic domain (DcR1) or contain a truncated death domain (DcR2). The standard product used in this kit is recombinant human TRAIL with the molecular mass of 21KDa. It is expressed from the amino acids ectoderm T95--G281.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 1 pg/mL
TRAIL ELISA Kit (Human) (OKBB00266)
Aviva Systems BiologySupplier: Gentaur
Catalog: 247-OKBB00266
Stock:On request
Product Size: 96 Tests
You may also be interested
-
OKBB00266-96W - TRAIL ELISA Kit (Human)
Catalog Number: OKBB00266-96W -
KIT/SCFR ELISA Kit (Human) (OKBB00447)
Catalog Number: OKBB00447 -
KL ELISA Kit (Human) (OKBB01180)
Catalog Number: OKBB01180 -
EPO ELISA Kit (Human) (OKBB00694)
Catalog Number: OKBB00694 -
CA9 ELISA Kit (Human) (OKBB00777)
Catalog Number: OKBB00777
Add a review
TRAIL ELISA Kit (Human) (OKBB00266)
Catalog number: / Size: / Price: GBP (Excluded VAT)
0 reviews for Aviva Systems Biology