ELISA kit for Rabbit Macrophage scavenger receptor types I and II (MSR1)

Supplier: Gentaur

0.01 GBP
Catalog: 749-KTE90089-96T Stock:On request
Product Size: 96T

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Quantitative sandwich ELISA for measuring Rabbit Macrophage scavenger receptor types I and II (MSR1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.



MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008]


All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).


  • Reactivity: Rabbit
  • Sample types: serum, whole blood, plasma and other biological fluids
  • Detection range: Please inquire
  • Sensitivity: Please inquire Quantitative Sandwich ELISA
  • Method of detection: Colorimetric

This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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