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ELISA kit for Mouse 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1)

Supplier Abbkine · Catalog number: KTE71399-96T

Price

539.00EUR

Size
96T

Quantitative sandwich ELISA for measuring Mouse 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

  • Additional information:CYP27B1 isa member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.
  • Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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