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ELISA kit for Mouse DNA (cytosine-5)-methyltransferase 1 (DNMT1)

Supplier Abbkine · Catalog number: KTE71397-5platesof96wells

Price

2115.00EUR

Size
5 plates of 96 wells

Quantitative sandwich ELISA for measuring Mouse DNA (cytosine-5)-methyltransferase 1 (DNMT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

  • Additional information:DNA (cytosine-5)-methyltransferases (DNMTs), such as DNMT1, maintain patterns of methylated cytosine residues in the mammalian genome. Genomic methylation patterns are reshaped during gametogenesis and early development and undergo programmed alterations during cellular differentiation. Methylation patterns are responsible for the repression of parasitic sequence elements and the expression status of genes subject to genomic imprinting and X inactivation. Faithful maintenance of methylation patterns is required for normal mammalian development, and aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.A DNMT1 enzyme is thought to be responsible for most of the maintenance as well as the de novo methylation activities occurring in the somatic cells of vertebrates.
  • Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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