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ELISA kit for Mouse Angiopoietin-related protein 4 (ANGPTL4)

Supplier Abbkine · Catalog number: KTE71376-5platesof96wells

Price

2115.00EUR

Size
5 plates of 96 wells

Quantitative sandwich ELISA for measuring Mouse Angiopoietin-related protein 4 (ANGPTL4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

  • Additional information:ANGPTL4 (Angiopoietin Like 4) is a Protein Coding gene. Diseases associated with ANGPTL4 include Plasma Triglyceride Level Qtl, Low and Severe Nonproliferative Diabetic Retinopathy. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Metabolism. GO annotations related to this gene include enzyme inhibitor activity. An important paralog of this gene is ANGPTL3. Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
  • Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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