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Novel Coronavirus COVID-19 (2019-nCoV) Real Time RT-PCR Kit
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ELISA kit for Mouse DNA (cytosine-5)-methyltransferase 3B (DNMT3B)

Supplier Abbkine · Catalog number: KTE71227-96T

Price

539.00EUR

Size
96T

Quantitative sandwich ELISA for measuring Mouse DNA (cytosine-5)-methyltransferase 3B (DNMT3B) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

  • Additional information:DNMT3B, is a protein associated with immunodeficiency, centromere instability and facial anomalies syndrome. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
  • Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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