Image of ELISA kit for Human Apoptosis protease activating factor-1 (APAF1)

ELISA kit for Human Apoptosis protease activating factor-1 (APAF1)

Supplier Abbkine · Catalog number: KTE62504-5platesof96wells


2252.00 EUR

5 plates of 96 wells
  • Reactivity: Human
  • Sample types: serum, whole blood, plasma and other biological fluids
  • Detection range: Please inquire
  • Sensitivity: Please inquire Quantitative Sandwich ELISA
  • Method of detection: Colorimetric
This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment. Apoptotic peptidase activating factor 1 is a proteincontains several copies of the WD40 repeat domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. The precise mechanism for this reaction is still debated though work published by Guy Salvesen suggests that the apoptosome may induce caspase 9 dimerization and subsequent autocatalysis. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis.Alternative splicing results in several transcript variants encoding different isoforms. All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).

* The price of the product is approximate, please contact us for price confirmation

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