Quantitative sandwich ELISA for measuring Human Apoptosis regulatory protein Siva (SIVA1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
CD27BP encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.Sequence analysis predicted that the 189-amino acid protein has an N-terminal ring finger and a cys-rich C terminus containing death domains with homology to those in FADD and RIP, as well as motifs that may form a B box-like ring finger, although it lacks his residues and coiled-coil domain structures. Northern blot analysis revealed ubiquitous expression of a 0.8-kb transcript that was greatest in thymus and lowest in colon.
All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
- Reactivity: Human
- Sample types: serum, whole blood, plasma and other biological fluids
- Detection range: Please inquire
- Sensitivity: Please inquire Quantitative Sandwich ELISA
- Method of detection: Colorimetric
This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.
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