LYVE-1 Recombinant Protein

Supplier ProSci · Catalog number: 91-539

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714.30 EUR

0.05 mg
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
  • Specifications:
    • Tested Applications: N/A
    • Applications: This recombinant protein can be used for biological assays. For research use only.
    • Predicted Molecular Weight: 24.6 kD
    • Physical state: Lyophilized
    • Buffer: Lyophilized from a 0.2 um filtered solution of 20mM Tris-Citrate,1 50mM NaCl, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
    • Concentration: N/A
    • NCBI official symbol: LYVE1
    • Accession #: Q9Y5Y7
    • Protein GI: N/A
    • NCBI gene ID#: 10894
    • NCBI official full name: lymphatic vessel endothelial hyaluronan receptor 1
    • NCBI organism: Homo sapiens
    • SWISSPROT #: Q9Y5Y7
    • Background Reference 1: N/A
    • Background Reference 2: N/A
    • Background Reference 3: N/A
    • Background Reference 4: N/A
    • Background Reference 5: N/A
    • Source: Human Cells
    • Species: Human
    • By Source: Human Cells
    • By Species: Human
    • Fusion tag: C-6 His tag
    • Sequence: Leu20-Thr238
    • Biology activity: N/A
    • Purity: Greater than 95% as determined by reducing SDS-PAGE.
      Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Storage and shipping:Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at -20°C for 3 months.
  • Notes:Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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