Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 µg/mL in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid nonglycosylated polypeptide, which contains an 18 amino acid N-terminal sequence. Recombinant human apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues.
The lyophilized Apo-SAA1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Apo-SAA1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Apo-SAA1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Tested Applications: N/A
- Applications: N/A
- Predicted Molecular Weight: N/A
- Physical state: Lyophilized
- Buffer: N/A
- Concentration: N/A
- NCBI official symbol: SAA1
- Accession #: NP_000322.2
- Protein GI: 40316912
- NCBI gene ID#: 6288
- NCBI official full name: serum amyloid A1
- NCBI organism: Homo sapiens
- Peptide sequence: MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
- SWISSPROT #: P0DJI8
- Background Reference 1: N/A
- Background Reference 2: N/A
- Background Reference 3: N/A
- Background Reference 4: N/A
- Background Reference 5: N/A
- Source: E. coli
- Species: Human
- By Source: E. Coli
- By Species: Human
- Fusion tag: N/A
- Sequence: MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
- Biology activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0 - 10.0 ng/mL.
- Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Endotoxin level is less than 0.1 ng per µg (1EU/µg).
This product is for research use only.
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