Multidrug resistance is the insensitivity or resistance of a microorganism to the administered antimicrobial medicines with different structures and the molecular formula (Tanwar, Das, Fatima, & Hameed, 2014). According to the World Health Organization (WHO), the resistant microorganisms that include bacteria, fungi, viruses, and parasites are able to fight the antimicrobial drugs. As a result, the antimicrobial drugs become ineffective in treating microbial infections leading to persistence and spreading of infections.
The emergence of resistance among various microbial species to different antimicrobial drugs has caused a public health threat all over the world. The development of multidrug resistance is a natural process, although, it can be due to inappropriate use of antimicrobial drugs, lack of adequate sanitary conditions, inappropriate food handling, and poor infection prevention and control practices. These factors encourage the further spread of multidrug resistance