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Pubmed ID :23511033
Publication Date : //

Syndecan-1 and heparanase: potential markers for activity evaluation and differential diagnosis of Crohn's disease.


Syndecan-1 (SDC1) and its endo-beta-D-glucuronidase heparanase (HPA) are implicated in the maintenance of intestinal barrier function, but their detailed functions in Crohn's disease (CD) are not fully investigated. The aim of this study was to determine alteration patterns of SDC1 and HPA and their potential roles in evaluating disease activity and differentiating CD from intestinal tuberculosis (ITB).

Authors : Zhang Shaoheng , Qing Qing , Wang Qunying , Xu Jun , Zhi Fachao , Park Pyong W , Zhang Yali , Chen Ye ,

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