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Index / Biovis / Caspase_7 Monoclonal Ab100 ug / Product Detail : 3010-100 Caspase_7 Monoclonal Ab100 ug
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Nov
18th

#3010-100 Caspase_7 Monoclonal Ab100 ug

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  Price : 395   EUR
449   USD
307   GBP
1662   Zloty
52961   JPY
3052   NOK
3270   SEK
447   CHF

Product name : Caspase_7 Monoclonal Ab100 ug

Catalog number : 3010-100

Quantity: 100 ug

Availability: Yes

Supplier name : Biovis

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About this Product :

Caspase_7 Monoclonal Ab100 ug http://biotech-map.com/aa_search/table_sample.html?q=monoclonal&filter=
Description
Caspase_7 Monoclonal Ab100 ug is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.

More Details about

HOST: Mouse
ISOTYPE: IgG1
CLONE: B4-G2
SPECIES REACTIVITY: human, mouse, rat
ANTIBODY FORMULATION:
100 μg (0.5 mg/ml) in PBS containing 1 mg/ml BSA and 1.5 mM thimerosal and 50% glycerol.
STORAGE CONDITIONS:
Store at -20°C. For long term storage, aliquot and refreeze at –70°C. Avoid repeated freeze/defrost cycles.
DESCRIPTION:
The caspase family of cysteine proteases plays a key role in apoptosis. Caspase-7, also known as Mch3α , ICE/LAP3 and CMH1, is a 34 kDa protein that is activated during Fas- and TNF-induced apoptosis. Caspase-7 has been identified as a major contributor to the execution phase of cellular apoptosis. It cleaves essential cellular machinery following its own cleavage from an inactive proenzyme to an active heterodimeric form. Caspase-7 is processed by caspase-3, -6, -8, -9, and –10 as well as by Granzyme B.
APPLICATIONS AND USAGE:
Western blot analysis (0.5-2 μg/ml) and immunoprecipitation (4-10 μg/ml). However the optimal conditions should be determined individually.
SPECIFICITY:
Detects both pro-caspase-7 (34 kDa) and the large subunit of cleaved caspase-7 (19 kDa) in apoptosis cells on SDS-PAGE immunoblots.

 

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